In a randomized controlled trial, 213 adult treatment-seeking smokers were randomized to receive nicotine patch therapy and 12 weeks of either computerized CT or computerized relaxation (control) training via MyBrainSolutions (now called Total Brain). This trial found that adjunctive cognitive training did not increase the likelihood of successful quitting, compared to an active control condition. Six month quit rates in both groups were similar to those reported in the literature for nicotine replacement therapy alone and there was no evidence for reductions in subjective withdrawal or craving symptoms during the quit attempt (Loughead, J., Falcone, M., Wileyto, E. P., Albelda, B., Audrain-McGovern, J., Cao, W., … Lerman, C. 2016. https://doi.org/10.1016/j.drugalcdep.2016.08.621)
A 2010 study evaluated whether Self Regulation training influences workplace productivity. 5,550 employees from major corporations were recruited to participate. They were required to complete 20 minutes of brain training 3x/week for 30 days. Those who completed the requirement in training (N=175), demonstrated a significant improvement in their self regulation score after 30 days. Workers with higher capacity for self regulation scored higher for workplace productivity (O’Connor, Megan & Cooper, Nicholas & Williams, Leanne & Devarnney, Savannah & Gordon, Evian. 2010. Neuroleadership and the Productive Brain.)
In another study, 2,751 participants used MyBrainSolutions (now called Total Brain) and their cognitive and emotional states were compared to a database of healthy norms. The most significant benefits were found for games training positivity to improve scores within anxiety, stress, and depression (feeling scores). In addition, training in self-regulation was found to be beneficial in terms of improved memory, attention, and executive function and reduction in anxiety, stress, and depression levels (Gordon, E., Palmer, D. M., Liu, H., Rekshan, W., & DeVarney, S. 2013. https://doi.org/info:doi/10.3727/194982413X13608676060574)